Satdarshan Pal Singh Monga / LinkedIn
The University of Pittsburgh School of Medicine appointed Indian-origin physician-scientist Satdarshan Pal Singh Monga as chair of its department of pharmacology and chemical Biology.
The university described Monga as an internationally recognized physician-scientist whose research has transformed the understanding of liver biology, regeneration and disease.
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Monga currently serves as the senior vice chancellor chair in Pathobiology and Therapeutics, professor of pharmacology and medicine, director of the Organ Pathobiology and Therapeutics Institute (OPTIn), director of the Pittsburgh Liver Research Center, associate dean of research at the School of Medicine, and program director of the Cellular Approaches to Tissue Engineering & Regeneration (CATER) Program.
Reacting to the announcement, Monga wrote on social media, "Truly a privilege! Looking forward to serving our faculty and our institution."
In 2024, Monga was appointed inaugural director of the Organ Pathobiology and Therapeutics Institute and associate dean of research at the School of Medicine. He succeeds in the new role while continuing to lead several major research initiatives at the university.Monga's research focuses on the cellular and molecular mechanisms that regulate liver development, regeneration, metabolism and cancer.
His laboratory has pioneered studies on Wnt/β-catenin signaling, liver repair and precision therapies for liver disease, using advanced techniques including single-cell and spatial omics, genetically engineered mouse models and intravital microscopy.
His work has been funded continuously by the National Institutes of Health and industry since 2003. He has authored more than 230 peer-reviewed publications in journals including Hepatology, Gastroenterology, Journal of Hepatology, Cell Metabolism, Cell Reports, Nature and others.
Among his recent contributions, Monga's team has helped develop potential precision therapies for liver cancer, including approaches targeting β-catenin-driven hepatocellular carcinoma that have advanced to clinical trials.
In addition to his research, Monga serves as president of the American Society for Investigative Pathology. He is editor-in-chief of Seminars in Liver Disease and serves as an associate or consulting editor for Science Signaling, Annual Reviews in Pathology and JCI Insights. He has also been inducted into the American Society for Clinical Investigation and the Association of American Physicians.
Monga joined the University of Pittsburgh in 1999 and has held a series of leadership positions, including division director of Experimental Pathology, vice chair of Experimental Pathology, assistant dean for the Medical Scientist Training Program and founding director of the Pittsburgh Liver Research Center, which has been supported by the National Institute of Diabetes and Digestive and Kidney Diseases since 2019.
He earned his Doctor of Medicine degree from Dayanand Medical College and Hospital, affiliated with Punjab University in Chandigarh, India.
He later completed postdoctoral fellowships in gastroenterology, hepatology, and molecular biology at Georgetown University School of Medicine and the Fels Cancer Institute at Temple University Hospital before joining the University of Pittsburgh in 1999.
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