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Jagadeesh Ramasamy wins NIH replication prize
A University of Illinois Chicago researcher, Ramasamy was recognized for advancing rigor and reproducibility in biomedical sciences.
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Malvika Choudhary - Fri, 05, Jun 2026
- 16:24 EDT
- 36
Jagadeesh Ramasamy / LinkedIn/ Jagadeesh Ramasamy
Indian-origin scientist Jagadeesh Ramasamy was named a winner of the National Institutes of Health (NIH) Replication Prize, awarded to researchers advancing rigor and reproducibility in biomedical science.
Ramasamy was recognized in Track 2: Replication Exemplars, a category honoring scientists who have successfully integrated replication into their regular research practices and demonstrated measurable improvements in research rigor. Each Track 2 winner will receive a prize of up to $50,000.
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At the University of Illinois Chicago (UIC), Ramasamy serves as director of Bioscience Research in Hematology/Oncology and associate professor in the Department of Pediatrics. His laboratory focuses on mitochondrial biology, autophagy, systemic inflammation, biomarker discovery, and the development of non-opioid pain therapies.
One of the lab's notable findings was the discovery of abnormally retained mitochondria in red blood cells of patients with sickle cell disease, linking the phenomenon to elevated levels of reactive oxygen species and hemolysis.
The research group is currently investigating biomarkers that could help predict which patients are at greater risk of severe pain and support the development of treatments that reduce reliance on opioid medications.
Ramasamy's recent research has expanded into mitochondria-targeting therapeutics aimed at treating chronic inflammatory diseases and improving cellular longevity. According to his professional profile, the work has potential applications in aging, regenerative medicine, and chronic disease prevention.
With more than 20 years of experience in hematology, oncology, and translational medicine, Ramasamy has authored more than 30 peer-reviewed publications and led multiple NIH-funded projects. He has also been involved in global health initiatives through the World Health Organization.
Ramasamy joined UIC in 2009 as a Research Assistant Professor and later became Director of Bioscience Research in 2023. He was appointed Associate Professor in 2025. Prior to joining UIC, he held research and faculty positions at the University of Chicago and completed postdoctoral fellowships at the Dana-Farber Cancer Institute and the University of Chicago.
The NIH said the replication strategies developed by the Track 2 winners will be compiled and published as a publicly available resource later this year to help researchers improve the rigor and reproducibility of biomedical science.
Ramasamy earned a Ph.D. in Medical Biochemistry and a master's degree in Environmental Toxicology from the University of Madras Institute of Basic Medical Sciences. He later completed postdoctoral training at the Dana-Farber Cancer Institute and the University of Chicago.
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