Indian-origin researcher uncovers why breast cancer treatments stop working

The researchers found that it unexpectedly activates a group of genes that respond to the hormone estrogen. Some of these genes can help cancer cells withstand treatment and retain the capacity to begin growing again.

SHOM GOEL / SHOM GOEL VIA X

Researchers led by Indian-origin academic Shom Goel have discovered why breast cancer treatment stops working for some patients, uncovering the unexpected role of one of the body's most important cancer-fighting proteins.

The study — led by Associate Professor Shom Goel alongside Postdoctoral Research Fellows Dr. April Watt and Dr. Antonio Ahn at the Peter MacCallum Cancer Centre in Melbourne — revealed that the retinoblastoma (Rb) protein — long considered one of the body's natural brakes on cancer growth — has a more complex function than previously understood.

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