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Purvesh Khatri’s immune scoring system can guide critical care decisions
Findings from the Stanford study showed that patients with high lymphoid dysregulation often benefited from steroid treatments, improving survival rates.
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Pranavi Sharma - Sat, 04, Oct 2025
- 01:42 EDT
- 14
Purvesh Khatri / Stanford Medicine
Stanford Medicine researcher Purvesh Khatri has developed a blood-based scoring system that could help doctors quickly decide how to treat patients with life-threatening conditions such as sepsis, trauma, burns, or respiratory distress. Khatri, an Indian-origin professor of biomedical informatics, detailed the findings in two papers published in Nature Medicine on Sept. 30.
The research builds on earlier work showing that immune cell gene “signatures” can diagnose infections and predict severity. This year, the U.S. Food and Drug Administration cleared a clinical test, known as TriVerity, based on those findings. TriVerity measures the activity of 29 genes to determine the likelihood of bacterial or viral infection and whether a patient is likely to require intensive care.
ALSO READ: Indian-origin scientist identifies immune cells linked to chronic inflammation and aging
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