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Shipra Arya receives American Heart Association grant

Her project develops an automated Peripheral Artery Calcium Score using deep learning to improve diagnosis, risk stratification, and outcomes.

Shipra Arya / Stanford University

The American Heart Association (AHA) has awarded a $300,000 grant to Indian-American surgeon and academician Shipra Arya. 

Arya, a professor of surgery at Stanford University School of Medicine and section chief of vascular surgery at the VA Palo Alto Healthcare System, will utilize the three-year transformational project award to develop an automated tool to improve diagnosis, risk stratification, and treatment strategies for peripheral artery disease (PAD) patients. 

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The project, titled Automated Peripheral Artery Calcium Score for Risk Stratification and Outcome Prediction in Peripheral Artery Disease, seeks to establish a fully automated Peripheral Artery Calcium Score (PACS) using deep learning techniques to quantify calcium deposits in lower extremity CT scans. 

From July 2025 through June 2028, researchers will evaluate PACS against current diagnostic standards such as the ankle-brachial index and toe-brachial index, while also measuring its predictive accuracy for outcomes including mortality, amputation, and major adverse limb events.

“This project is the first step toward integrating automated PACS into diagnosis, risk stratification, and treatment for PAD—similar to how coronary artery calcium scoring has transformed the care of coronary artery disease,” Arya said.

The interdisciplinary research team includes Akshay Chaudhari (biomedical data science), Fatima Rodriguez (cardiology), research manager Jillian Melbourne, and medical student Benjamin Liu. Together, they aim to develop and validate advanced deep learning models capable of eliminating the need for manual or semi-automated measurements, streamlining clinical workflows.

Arya, a graduate of the All India Institute of Medical Sciences with advanced training at Harvard, Creighton University, and the University of Michigan, has an extensive track record in surgical quality improvement and patient-centered care. She currently leads multiple national research initiatives, including the VA-funded PAUSE trial, and serves as president of the Surgical Outcomes Club.
 

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